Monitoring of radiation-induced germline mutation in humans.
نویسنده
چکیده
Estimating the genetic hazards of radiation and other mutagens in humans depends on extrapolation from experimental systems. Recent data have shown that minisatellite loci provide a useful and sensitive experimental approach for monitoring radiation-induced mutation in humans. This review describes the progress made in validating this approach and presents the results of recent publications on the analysis of minisatellite mutation rates in the irradiated families.
منابع مشابه
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ورودعنوان ژورنال:
- Swiss medical weekly
دوره 133 35-36 شماره
صفحات -
تاریخ انتشار 2003